ADVENTRX PHARMACEUTICALS, INC. & BIODEL, INC.

***We no longer follow the companies mentioned in these backdated newsletter issues. These samples of past newsletters are generated to give you an idea of what you can expect when you subscribe. Please do not use any of the information contained in the samples below as current advice. If you would like to purchase a newsletter subscription, please click here. ***

Hello Readers,

Since the last Newsletter, we closed five more positions; three for a nice gains and two for losses.

TENGION (1/20/11). Closed position 2/14/11 at $5.09 for a 70% GAIN.

SOLTA MEDICAL (10/5/09). Closed position 2/15/11 at $3.56 for a 70% GAIN.

TRANSITION THERAPEUTICS (2/5/11). Closed position 2/15/11 at $3.20 for a 55% GAIN.

SUNESIS PHARMA (11/5/07). Closed position 2/14/11 at 42 cents for a 84% LOSS.

AKEENA SOLAR (10/20/08). Closed position 2/15/11 at 53 cents for a 77% LOSS.

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NETWORK ENGINES, INC. & TRANSITION THERAPEUTICS, INC.

***We no longer follow the companies mentioned in these backdated newsletter issues. These samples of past newsletters are generated to give you an idea of what you can expect when you subscribe. Please do not use any of the information contained in the samples below as current advice. If you would like to purchase a newsletter subscription, please click here. ***

Hello Readers,

Since the last Newsletter, we closed four more positions; three for gains and one for a loss.

TII NETWORK TECHNOLOGIES (3/20/06). Closed position 1/27/11 at $3.55 for a 51% GAIN.

I.D. SYSTEMS (12/5/10). Closed position 1/18/11 at $4.16 for a 60% GAIN.

CEREPLAST (12/20/10). Closed position 1/19/11 at $5.95 for a 51% GAIN.

A.P. PHARMA (8/5/07). Closed position 1/18/11 at 58 cents for a 75% LOSS.

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REAL GOODS SOLAR, INC. & TENGION, INC.

***We no longer follow the companies mentioned in these backdated newsletter issues. These samples of past newsletters are generated to give you an idea of what you can expect when you subscribe. Please do not use any of the information contained in the samples below as current advice. If you would like to purchase a newsletter subscription, please click here. ***

Hello Readers,

Since the last Newsletter, we closed nine more positions; seven for gains and two for a losses.

AMICUS THERAPEUTICS (10/5/10). Closed position 1/14/11 at $6.30 for a 64% GAIN.

THRESHOLD PHARMACEUTICALS (8/5/10). Closed position 1/14/11 at $2.18 for a 56% GAIN.

MARKET LEADER (12/20/08). Closed position 1/13/11 at $2.98 for a 78% GAIN.

ZELICUS (5/5/10). Closed position 1/11/11 at $2.40 for a 67% GAIN.

PHC (5/20/10). Closed position 1/11/11 at $1.84 for a 52% GAIN.

ACADIA PHARMACEUTICALS (9/5/10). Closed position 1/10/11 at $1.64 for a 63% GAIN.

ORBCOMM (9/5/10). Closed position 1/6/11 at $3.10 for a 67% GAIN.

UROLOGIX (2/20/07). Closed position 1/13/11 at 76 cents for a 78% LOSS.

HESKA (7/5/07). Closed position 1/3/11 at $4.95 for a 79% LOSS. (price reflects reverse split).

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GREAT BASIN GOLD LTD. & SPRINT NEXTEL CORPORATION

***We no longer follow the companies mentioned in these backdated newsletter issues. These samples of past newsletters are generated to give you an idea of what you can expect when you subscribe. Please do not use any of the information contained in the samples below as current advice. If you would like to purchase a newsletter subscription, please click here. ***

Happy 2011 Readers!

Since the last Newsletter, we closed eight more positions; five for gains and three for losses.

ACHILLION PHARMACEUTICALS (3/5/10). Closed position 12/23/10 at $3.64 for a 58% GAIN.

PEREGRINE PHARMACEUTICALS (11/5/10). Closed position 12/23/10 at $2.35 for a 55% GAIN.

CLEARFIELD (6/5/10). Closed position 12/20/10 at $4.38 for a 70% GAIN.

AETERNA ZENTARIS (6/20/10). Closed position 12/20/10 at $2.00 for a 53% GAIN.

DURECT CORP (4/20/09). Closed position 12/20/10 at $3.67 for a 53% GAIN.

HELICOS BIOSCIENCES (10/20/09). Closed position 12/13/10 at 16 cents for a 94% LOSS.

OXIGENE (10/20/09). Closed position 12/23/10 at 22 cents for a 83% LOSS.

NTN BUZZTIME (7/5/06). Closed position 12/23/10 at 39 cents for a 73% LOSS.

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TRIDENT MICROSYSTEMS, INC. & CEREPLAST, INC.

***We no longer follow the companies mentioned in these backdated newsletter issues. These samples of past newsletters are generated to give you an idea of what you can expect when you subscribe. Please do not use any of the information contained in the samples below as current advice. If you would like to purchase a newsletter subscription, please click here. ***

Hello Readers,

Since the last Newsletter, we closed six more positions; four for gains and two for losses.

ENDOLOGIX (1/20/07). Closed position 12/15/10 at $6.88 for a 62% GAIN.

WILLDAN GROUP (5/20/10). Closed position 12/9/10 at $4.00 for a 60% GAIN.

INVENTURE FOODS (3/5/06). Closed position 12/9/10 at $4.47 for a 54% GAIN.

U.S. HOME SYSTEMS (8/20/10). Closed position 12/7/10 at $4.75 for a 58% GAIN.

XENOMICS (6/5/07). Closed position 12/7/10 at 45 cents for a 82% LOSS.

HARBOR BIOSCIENCES (12/20/07). Closed position 12/7/10 at 15 cents for a 92% LOSS.

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I.D. SYSTEMS, INC. & SUPERGEN, INC.

***We no longer follow the companies mentioned in these backdated newsletter issues. These samples of past newsletters are generated to give you an idea of what you can expect when you subscribe. Please do not use any of the information contained in the samples below as current advice. If you would like to purchase a newsletter subscription, please click here. ***

Hello Readers,

Since the last Newsletter, we closed two positions; one for a gain and the other for a loss.

SINOHUB (9/20/10). Closed position 11/22/10 at $3.23 for a 63% GAIN.

LIGAND PHARMA (2/20/09). Closed position 11/19/10 at $9.07 for a 42% LOSS.

SinoHub, which had done well ever since we picked it, got a nice upward push after releasing a half-decent earnings report. We closed Ligand Pharmaceuticals after it did the 1 for 6 reverse split, which, as we have said over the years, these seldom work for current shareholders.

The markets have looked precarious over the last several weeks thanks to concerns over the crisis on the Korean Peninsula, the fate of the Bush tax cuts, Ireland, Portugal, and Spain. There are a few other concerns that can be thrown into the mix, but why dwell on them? The one thing to watch for is that the much-anticipated Santa Claus rally may not happen. Actually, if there isn’t a deal on the tax cuts, soon, the markets could get real dicey.

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PEREGRINE PHARMACEUTICALS, INC. & RELM WIRELESS CORPORATION

Hello Readers,

Within two days after this Newsletter is posted, the markets will face new realities. The first is that the Democratic Congressional money spigot, while maybe not slowing to a trickle, will not be the constant gusher that Wall Street has reveled in for the last several years. The other truth is that the Fed may very well make up for any Congressional shortcomings. In other words, as one printing press slows down, the other revs up even more. The funny-money has been keeping the markets juiced for the last 20 months. How much longer can things keep going up before asset bubbles go pop? Honestly, we are still surprised that the party has continued for this long, which begs the question: How bad are things in the underlying economy that makes the Fed feel compelled to continued quantitative easing? What do Chairman Ben and company know that we don’t?

Our Current Portfolio has improved somewhat over the past few weeks, but, like the Russell 2000 Index, which measures small stock performance, has not enjoyed the same upturn as mid and big cap stocks.

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INOVIO PHARMACEUTICALS, INC. & BLUE PHOENIX SOLUTIONS, LTD.

***We no longer follow the companies mentioned in these backdated newsletter issues. These samples of past newsletters are generated to give you an idea of what you can expect when you subscribe. Please do not use any of the information contained in the samples below as current advice. If you would like to purchase a newsletter subscription, please click here. ***

Hello Readers,

Since the last Newsletter, we closed three more positions, all were for gains that were below our 50%-plus standard because they were all buyouts, or soon-to-be acquired.

SALARY.COM (7/5/09). Closed position 10/1/10 at $4.06 for a 35% GAIN.

MICROTUNE (2/5/10). Closed position 10/15/10 at $2.92 for a 32% GAIN.

ACTIVIDENTITY (3/5/08). Closed position 10/15/10 at $3.23 for a 6% GAIN.

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AMICUS THERAPEUTICS, INC & PROPHASE LABS, INC.

***We no longer follow the companies mentioned in these backdated newsletter issues. These samples of past newsletters are generated to give you an idea of what you can expect when you subscribe. Please do not use any of the information contained in the samples below as current advice. If you would like to purchase a newsletter subscription, please click here. ***

Hello Readers,

The markets are currently trading at the upper end of that trading range everyone’s been talking about, despite even more bad economic numbers. Two forces appear to be helping, for now. First is that the Fed keeps signaling that it will keep pumping funny money into the system regardless of future consequences. The second factor is the prospect of a big Republican victory next month, which, presumably would slow Congress’s massive spending spree. Remember 2001 to 2007 when the GOP controlled everything? They did pretty much what the Democrats are now doing. October’s market action should be all about earnings news, but who knows? We haven’t closed any positions over the last few weeks, but much of our Current Portfolio is looking less bad, to paraphrase the “new normal”.

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SINOHUB, INC. ADVANCED ANALOGIC TECHNOLOGIES, INC.

***We no longer follow the companies mentioned in these backdated newsletter issues. These samples of past newsletters are generated to give you an idea of what you can expect when you subscribe. Please do not use any of the information contained in the samples below as current advice. If you would like to purchase a newsletter subscription, please click here. ***

Hello Readers,

Maybe we should change our name to “Penny Stock Buyouts”, because, as you will see in the below updates, another one of our picks is pending acquisition. This makes an even half-dozen over the last several months, and, thankfully, except for one of them, all the buyout offers meant some sort of gains. So, what’s happening? We suspect the markets have entered some sort of consolidation phase, which is typical of bearish cycles. However, we have never seen this sort of acquisition activity among penny stocks. Obviously, many larger companies with money to burn are picking off smaller companies at what some would consider to be fire sale prices.

The market is still stuck in a 500 to 600 point trading range due to a lot of uncertainties. We need not tell you what those are, since you probably already know. The best word to describe the current market action is “hinky”, for lack of a better description. People have the feeling that a lot of things just are not right, despite all of the glowing adjectives that politicians and certain gurus have been throwing around. And yes, the current funk has not been helping our Current Portfolio at all.

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