NEUROMETRIX, INC. & CERUS CORPORATION

***We no longer follow the companies mentioned in these backdated newsletter issues. These samples of past newsletters are generated to give you an idea of what you can expect when you subscribe. Please do not use any of the information contained in the samples below as current advice. If you would like to purchase a newsletter subscription, please click here. ***

Hello Readers,

We did not close any positions since the last Newsletter, and, as many of you know, these droughts happen, periodically, though not often. Thanks to the updraft in the markets over the last few weeks, many of our Current Positions strengthened, particularly those picks of the last year or so. Why the mini-surge in the markets? Pretty simple to answer, still. Rates are at zero and many future calamities are being postponed by various banks and governments around the globe; the most recent that was placed on cruise control was the Greek Crisis. What we are witnessing is perhaps the only time in our nation’s history when the markets are not in sync with the realities of the pending disasters. It is also the only time that we can remember such horrible contortions in the markets thanks to government intervention. So, in the meantime, enjoy the ride, but, as we have been stressing for months, be afraid, be very very afraid.

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ACHILLION PHARMACEUTICALS, INC. & CLARIENT, INC.

***We no longer follow the companies mentioned in these backdated newsletter issues. These samples of past newsletters are generated to give you an idea of what you can expect when you subscribe. Please do not use any of the information contained in the samples below as current advice. If you would like to purchase a newsletter subscription, please click here. ***

Hello Readers,

Since the last Newsletter, we closed two more positions; one for a gain and one for a loss. We will be posting them, soon, on the Track Record page.

MAKE MUSIC, INC. (1/20/09). Closed position 2/22/10 at $5.76 for a 52% GAIN.

AMERITYRE (12/5/07). Closed position 2/22/10 at 52 cents for a 77% LOSS.

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ROSETTA GENOMICS LTD. & ZAGG, INC.

***We no longer follow the companies mentioned in these backdated newsletter issues. These samples of past newsletters are generated to give you an idea of what you can expect when you subscribe. Please do not use any of the information contained in the samples below as current advice. If you would like to purchase a newsletter subscription, please click here. ***

Hello Readers,

Since the last Newsletter, we closed another position:

Pharmacyclics (6/20/07). Closed position 2/9/10 at $5.00 for a 62% GAIN.

Here’s another that worked thanks to a lot of patience. Back in March, 2008, Pharmacyclics had sunk to 65 cents, but we hung in there because its balance sheet did. Over recent months, the stock got a nice boost probably due to the mini rebirth in biotechs, along with some upbeat clinical trial news and a brokerage house “buy” signal.

The markets keep drifting down. One day the Dow is up 180 points and then down 250 over the next two. We sense this will be the pattern for quite some time. Investors are starting to realize that any real economic rebound is in the distant future. We do not foresee any massive panic selling in the near-term, but, sometime, over the next six to twelve months, look for it. There are still too many adversities keeping a damper on things; we need not give a list, since you have heard them all. At some point, all of these components will converge at once, creating a “perfect storm of selling.”

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MICROTUNE, INC. & CYTOKINETICS, INC.

***We no longer follow the companies mentioned in these backdated newsletter issues. These samples of past newsletters are generated to give you an idea of what you can expect when you subscribe. Please do not use any of the information contained in the samples below as current advice. If you would like to purchase a newsletter subscription, please click here. ***

Hello Readers,

Since the last Newsletter, we closed three more positions; two for gains and one for a loss.

PLX TECHNOLOGIES (12/20/09). Closed position 1/27/10 at $5.17 for a 60% GAIN.

WAVE SYSTEMS (9/5/07). Closed position 1/19/10 at $2.85 for a 78% GAIN.

LANTRONIX (12/5/06). Closed position 1/19/10 at $3.69 for a 58% LOSS.

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CHELSEA THERAPEUTICS INT’L, LTD. & NIV INTELLIMEDIA TECHNOLOGY GROUP, INC.

***We no longer follow the companies mentioned in these backdated newsletter issues. These samples of past newsletters are generated to give you an idea of what you can expect when you subscribe. Please do not use any of the information contained in the samples below as current advice. If you would like to purchase a newsletter subscription, please click here. ***

Hello Readers,

Since the last Newsletter, we closed four more positions; three for gains and one for a loss.

ADEPT TECHNOLOGY (9/5/09). Closed position 1/14/10 at $3.85 for a 50% GAIN.

CYCLACEL PHARMA (1/5/10). Closed position 1/7/10 at $1.85 for a 81% GAIN.

OCCAM NETWORKS (8/5/09). Closed position 1/6/10 at $5.96 for a 54% GAIN.

ORE PHARMA (4/20/07). Closed position 1/6/10 at 55 cents for a 95% LOSS. (price reflects reverse split)

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CYCLACEL PHARMACEUTICALS, INC. & CYTRX CORPORATION

***We no longer follow the companies mentioned in these backdated newsletter issues. These samples of past newsletters are generated to give you an idea of what you can expect when you subscribe. Please do not use any of the information contained in the samples below as current advice. If you would like to purchase a newsletter subscription, please click here. ***

HAPPY NEW YEAR READERS! (we hope)

Since the last Newsletter, we did not close any positions, which is usually the case over the holidays. However, what was HIGHLY UNUSUAL was the number of positions we closed in 2009. The total number of Closed Positions was 70. To put it in better perspective, since our first Newsletter appeared on March 20, 1997, we have had 598 total Closed Positions, and nearly 12% of those came in one year. Of course, 2009 was a very unusual year, and we all know why. So, what happens this year? Look for the government to begin weaning itself from the market in the face of more joblessness, ever-declining housing values, and an increasing debt overload. It’s a dance that the Fed and Treasury may not be able to do, since we are in uncharted waters. Their actions will probably cause some choas leading to wild swings in the markets, both on the upside and downside. As Axl Rose once said, “Welcome to the jungle”.

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CORCEPT THERAPEUTICS, INC. & PLX TECHNOLOGY, INC.

***We no longer follow the companies mentioned in these backdated newsletter issues. These samples of past newsletters are generated to give you an idea of what you can expect when you subscribe. Please do not use any of the information contained in the samples below as current advice. If you would like to purchase a newsletter subscription, please click here. ***

Hello Readers,

Since the last Newsletter, we closed six more positions; four for gains and two for losses.

DYNAVAX (11/5/09). Closed position 12/10/09 at $1.94 for a 55% GAIN.

TIGERLOGIC (11/5/09). Closed position 12/9/09 at $4.50 for a 50% GAIN.

CONTINUCARE (11/20/07). Closed position 12/8/09 at $3.96 for a 55% GAIN.

DRUGSTORE.COM (9/5/09). Closed position 12/8/09 at $3.55 for a 50% GAIN.

THERMOGENESIS (4/5/06). Closed position 12/8/09 at 59 cents for a 85% LOSS.

RAE SYSTEMS (10/5/05). Closed position 12/8/09 at 73 cents for a 78% LOSS.

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REAL GOODS SOLAR, INC. & ORCHID CELLMARK, INC.

***We no longer follow the companies mentioned in these backdated newsletter issues. These samples of past newsletters are generated to give you an idea of what you can expect when you subscribe. Please do not use any of the information contained in the samples below as current advice. If you would like to purchase a newsletter subscription, please click here. ***

Hello Readers,

Since the last Newsletter, we closed three more positions; two for gains and one for a loss.

AMICAS (1/20/08). Closed position 11/27/09 at $4.72 for a 65% GAIN.

EVOLUTION PETROLEUM (8/20/09). Closed position 11/17/09 at $4.48 for a 52% GAIN.

NUCRYST PHARMA (10/5/07). Closed position 11/17/09 at $1.76 for a 42% LOSS.

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OXIGENE, INC. & URANERZ ENERGY CORPORATION

***We no longer follow the companies mentioned in these backdated newsletter issues. These samples of past newsletters are generated to give you an idea of what you can expect when you subscribe. Please do not use any of the information contained in the samples below as current advice. If you would like to purchase a newsletter subscription, please click here. ***

Hello Readers,

Since the last Newsletter, we closed four more positions; two for gains and two for losses.

INTEGRATED SILICON SOLUTION (6/20/09). Closed position 11/9/09 at $4.28 for a 65% GAIN.

ENDEAVOUR SILVER (9/5/08). Closed position 11/9/09 at $3.40 for a 50% GAIN.

NEUROBIOLOGICAL TECH (7/5/08). Closed position 11/2/09 at 93 cents for a 34% LOSS.

ECTEL (5/5/07). Closed position 11/2/09 at $1.24 for a 64% LOSS.

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TIGERLOGIC CORPORATION & DYNAVAX TECHNOLOGIES CORPORATION

***We no longer follow the companies mentioned in these backdated newsletter issues. These samples of past newsletters are generated to give you an idea of what you can expect when you subscribe. Please do not use any of the information contained in the samples below as current advice. If you would like to purchase a newsletter subscription, please click here. ***

Hello Readers,

Since the last Newsletter, we closed one position, for a gain.

THE HACKETT GROUP (4/20/09). Closed position 10/22/09 at $3.48 for a 56% GAIN.

For the last month, or so, The Hackett Group had climbed steadily and pierced our 50%-plus threshold on news that it had entered into a strategic alliance with South Africa’s IQ Business Group.

The fact that we only closed a single position over the last few weeks speaks volumes about the course of the markets during that time. Does the recent selloff mean that the reality of the economy has finally caught up to the markets’ psyche? With rates still a 0%, the unwarranted enthusiasm of the last seven months may start to resurface. But, at some point in the not-so-distant future, realities will really stick.

We should further add that the market downturn since mid-October has obviously put pressure on stocks in the Current Portfolio.

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